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Each one is tipped with microscopic backwards-facing barbs, which supposedly make it harder to pull the quills out once they’re stuck in.

That explains why punctured pooches need trips to the vet to denude their faces. Woo Kyung Cho from Harvard Medical School and Massachusetts Institute of Technology has found that the barbs also make it easier for the quills to impale flesh in the first place.

They dug into the soil, and ascended into the 40-metre-tall treetops with ropes, balloons, and a giant crane.

Both studies used the same methods to trigger neurons in the same part of the brain… In Tye and Mirzabekov’s experiment, depressed mice resumed their normal behaviour.

In Chaudhury and Walsh’s study, the resilient mice showed For the last 2.5 years, I have enjoyed a cosy symbiosis with Discover, providing bloggy sustenance in exchange for shelter, like many a gut bacterium.

It struggles when held aloft, it explores open areas, and it regains its sweet tooth. But on the other side of the country, at the Mount Sinai School of Medicine, Dipesh Chaudhury and Jessica Walsh are doing the same thing to completely different effect.

Their mice have been altered in a similar way, so that light can also switch on their VTA neurons.

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